Biology:B1 domain

From HandWiki
B1
PDB 1hez EBI.jpg
antibody-antigen complex
Identifiers
SymbolB1
PfamPF02246
InterProIPR003147
SMARTPB1
SCOP21ipg / SCOPe / SUPFAM

In molecular biology, the protein domain b1 refers to the domain b1 of Protein L. L is a bacterial protein with immunoglobulin (Ig) light chain-binding properties. It contains a number of homologous b1 repeats towards the N terminus. These repeats have been found to be responsible for the interaction of protein L with Ig light chains.[1] N-terminus domain contains five homologous B1 repeats of 72-76 amino acids each.[1]

References

  1. 1.0 1.1 "Structure of peptostreptococcal protein L and identification of a repeated immunoglobulin light chain-binding domain". J. Biol. Chem. 267 (18): 12820–5. June 1992. PMID 1618782. 
This article incorporates text from the public domain Pfam and InterPro: IPR003147