Biology:Adenain
From HandWiki
Short description: Class of enzymes
Adenain (EC 3.4.22.39) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-Xaa- and -Yaa-Xaa-Gly-Xaa-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid)
This cysteine endopeptidase is encoded by adenoviruses.
References
- ↑ "The adenovirus protease is activated by a virus-coded disulphide-linked peptide". Cell 72 (1): 97–104. January 1993. doi:10.1016/0092-8674(93)90053-s. PMID 8422686.
- ↑ "Crystal structure of the human adenovirus proteinase with its 11 amino acid cofactor". The EMBO Journal 15 (8): 1778–83. April 1996. PMID 8617222.
- ↑ Weber, J.M.; Rawlings, N.D.; Woessner, J.F. (1998). "Adenovirus protease". in Barrett, A.J.. Handbook of Proteolytic Enzymes. London: Academic Press. pp. 741–743.
External links
- Adenain at the US National Library of Medicine Medical Subject Headings (MeSH)
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