Biology:Acylagmatine amidase
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Short description: Class of enzymes
| acylagmatine amidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.5.1.40 | ||||||||
| CAS number | 39419-74-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an acylagmatine amidase (EC 3.5.1.40) is an enzyme that catalyzes the chemical reaction
- benzoylagmatine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] benzoate + agmatine
Thus, the two substrates of this enzyme are benzoylagmatine and H2O, whereas its two products are benzoate and agmatine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is benzoylagmatine amidohydrolase. Other names in common use include acylagmatine amidohydrolase, and acylagmatine deacylase.
References
- "Letter: Preparation of bleomycinic acid: hydrolysis of bleomycin B2 by a Fusarium acylagmatine amidohydrolase". The Journal of Antibiotics 26 (2): 117–9. February 1973. doi:10.7164/antibiotics.26.117. PMID 4131159.
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