Biology:ABCF1
 Generic protein structure example |
ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene.[1][2]
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.[2]
See also
References
- ↑ "ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes". Genomics 53 (2): 137–45. Dec 1998. doi:10.1006/geno.1998.5480. PMID 9790762.
- ↑ 2.0 2.1 "Entrez Gene: ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23.
Further reading
- "An inventory of the human ABC proteins.". Biochim. Biophys. Acta 1461 (2): 237–62. 2000. doi:10.1016/s0005-2736(99)00161-3. PMID 10581359.
- "Selective Translational Repression of Truncated Proteins from Frameshift Mutation-Derived mRNAs in Tumors". PLOS Biol. 5 (5): e109. 2007. doi:10.1371/journal.pbio.0050109. PMID 17456004.
- "Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis". Immunogenetics 59 (1): 45–52. 2007. doi:10.1007/s00251-006-0178-2. PMID 17119950.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. 2006. doi:10.1038/nbt1240. PMID 16964243.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics 3 (11): 1093–101. 2005. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
- "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. 2004. doi:10.1073/pnas.0404720101. PMID 15302935. Bibcode: 2004PNAS..10112130B.
- "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner". J. Biol. Chem. 275 (44): 34131–9. 2000. doi:10.1074/jbc.M002868200. PMID 10931828.
External links
- ABCF1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Human ABCF1 genome location and ABCF1 gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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