Biology:6-Phospho-β-glucosidase

From HandWiki
Short description: Class of enzymes
6-Phospho-β-glucosidase
Identifiers
EC number3.2.1.86
CAS number37205-51-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme 6-phospho-β-glucosidase (EC 3.2.1.86) catalyzes the following reaction:

6-phospho-β-D-glucosyl-(1,4)-D-glucose + H2O [math]\displaystyle{ \rightleftharpoons }[/math] D-glucose + D-glucose 6-phosphate

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 6-phospho-β-D-glucosyl-(1,4)-D-glucose glucohydrolase. Other names in common use include phospho-β-glucosidase A, phospho-β-glucosidase, and phosphocellobiase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1S6Y.

References

  • "Cellobiose metabolism in Aerobacter aerogenes. 3. Cleavage of cellobiose monophosphate by a phospho-β-glucosidase". J. Biol. Chem. 247 (11): 3420–3. 1972. PMID 4624114.