Biology:3-hydroxyanthranilate 4-C-methyltransferase
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Short description: Class of enzymes
| 3-hydroxyanthranilate 4-C-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.97 | ||||||||
| CAS number | 112445-22-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-hydroxyanthranilate 4-C-methyltransferase (EC 2.1.1.97) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 3-hydroxyanthranilate [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
Thus, the two substrates of this enzyme are S-adenosyl methionine and 3-hydroxyanthranilate, whereas its two products are S-adenosylhomocysteine and 3-hydroxy-4-methylanthranilate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase. This enzyme is also called 3-hydroxyanthranilate 4-methyltransferase.
References
- "Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase". J. Biol. Chem. 263 (10): 4602–6. 1988. PMID 2450873.
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