Biology:2-Formylbenzoate dehydrogenase

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Short description: Class of enzymes
2-Formylbenzoate dehydrogenase
Identifiers
EC number1.2.1.78
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

2-Formylbenzoate dehydrogenase (EC 1.2.1.78, 2-carboxybenzaldehyde dehydrogenase, 2CBAL dehydrogenase, PhdK) is an enzyme with systematic name 2-formylbenzoate:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

2-formylbenzoate + NAD+ + H2O [math]\displaystyle{ \rightleftharpoons }[/math] o-phthalic acid + NADH + H+

The enzyme is involved in phenanthrene degradation.

References

  1. "Biochemical and genetic characterization of 2-carboxybenzaldehyde dehydrogenase, an enzyme involved in phenanthrene degradation by Nocardioides sp. strain KP7". Journal of Bacteriology 179 (20): 6488–94. October 1997. PMID 9335300. 
  2. "Isolation and some properties of NAD-linked 2-carboxybenzaldehyde dehydrogenase in Alcaligenes faecalis AFK 2 grown on phenanthrene". J. Gen. Appl. Microbiol. 27: 443–455. 1981. doi:10.2323/jgam.27.443. 

External links