Biology:1-alkenyl-2-acylglycerol choline phosphotransferase

From HandWiki
Short description: Class of enzymes
1-alkenyl-2-acylglycerol choline phosphotransferase
Identifiers
EC number2.7.8.22
CAS number113066-36-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a 1-alkenyl-2-acylglycerol choline phosphotransferase (EC 2.7.8.22) is an enzyme that catalyzes the chemical reaction

CDP-choline + 1-alkenyl-2-acylglycerol [math]\displaystyle{ \rightleftharpoons }[/math] CMP + plasmenylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1-alkenyl-2-acylglycerol, whereas its two products are CMP and plasmenylcholine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase. This enzyme is also called CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase. This enzyme participates in ether lipid metabolism.

References

  • "Choline glycerophospholipid biosynthesis in the guinea pig heart". Biochem. Cell Biol. 65 (10): 860–8. 1987. doi:10.1139/o87-112. PMID 3447597.