Biology:(−)-Isopiperitenone reductase

From HandWiki
Short description: Class of enzymes
(−)-isopiperitenone reductase
Identifiers
EC number1.3.1.82
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

(−)-Isopiperitenone reductase (EC 1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase.[1][2] It catalyses the following chemical reaction:

(+)-cis-isopulegone + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] (−)-isopiperitenone + NADPH + H+

The reaction occurs in the opposite direction.

References

  1. "Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita)". Archives of Biochemistry and Biophysics 249 (2): 306–15. September 1986. doi:10.1016/0003-9861(86)90007-x. PMID 3755881. 
  2. "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics 418 (1): 80–92. October 2003. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086. 

External links