Biography:Eran Elhaik
Eran Elhaik | |
|---|---|
| Born | 1980 |
| Nationality | Israeli and American |
| Alma mater | University of Houston |
| Scientific career | |
| Fields | Genetics, bioinformatics, Population genetics |
| Institutions | Johns Hopkins University, University of Sheffield |
| Doctoral advisor | Dan Graur |
Eran Elhaik (born 1980 in Israel) is an Israeli-American geneticist and bioinformatician. His research uses computational, statistical, epidemiological and mathematical approaches to fields such as complex disorders, population genetics, personalised medicine, molecular evolution, genomics, paleogenomics and epigenetics.
Career
After completing undergraduate studies in Israel, he obtained a PhD in molecular evolution under the supervision of Dan Graur at the University of Houston in 2009, followed by postdoctoral research fellowships at the Johns Hopkins University School of Medicine and School of Public Health. Since 2014 he works at the University of Sheffield Department of Animal and Plant Sciences.[1]
Research
In the field of molecular evolution, Elhaik worked on the compositional domain model that describes the compositional organization of animal genomes.[2]
In the field of complex disorders, he proposed that the allostatic load theory could be used to explain bipolar disorder [3] and Sudden infant death syndrome (SIDS).[4] According to this theory, the accumulation of perinatal and prenatal stressors has neurotoxic effects with consequences to one's health.
In the field of genetics, Elhaik was part of the team that designed the GenoChip microarray for the Genographic Project and their online tests.[5] He also contributed to the development of algorithms for data compression.[6]
In the field of population genetics, Elhaik has published papers analyzing the ancestries of European Jews[7][8][9] and Druze,[10][11] including work related to the Khazar hypothesis of Ashkenazi ancestry, a contentious subject that has received media attention.[12] Elhaik argues for a non-Levantine origin of the Ashkenazi[13] and favours the hypothesis that they are of mixed Irano-Turko-Slavic and southern European descent.[14]
References
- ↑ "Dr Eran Elhaik". University of Sheffield. https://www.shef.ac.uk/aps/staff-and-students/acadstaff/elhaik.
- ↑ Elhaik, Eran; Graur, Dan; Josić, Krešimir; Landan, Giddy (2010). "Identifying compositionally homogeneous and nonhomogeneous domains within the human genome using a novel segmentation algorithm". Nucleic Acids Research 38 (15): e158. doi:10.1093/nar/gkq532. PMID 20571085.
- ↑ Elhaik, Eran; Zandi, Peter (2015). "Dysregulation of the NF-κB pathway as a potential inducer of bipolar disorder". Journal of Psychiatric Research 70: 18–27. doi:10.1016/j.jpsychires.2015.08.009. PMID 26424419.
- ↑ Elhaik, Eran (2016). "A 'Wear and Tear' Hypothesis to Explain Sudden Infant Death Syndrome". Frontiers in Neurology 7: 180. doi:10.3389/fneur.2016.00180. PMID 27840622.
- ↑ "Genome Biology and Evolution | Oxford Academic". http://gbe.oxfordjournals.org/content/5/5/1021.full.pdf+html.
- ↑ Chanda, P; Elhaik, E; Bader, JS (27 Jul 2012). "HapZipper: sharing HapMap populations just got easier". Nucleic Acids Research 40 (20): e159. doi:10.1093/nar/gks709. PMID 22844100. PMC 3488212. http://nar.oxfordjournals.org/content/40/20/e159.full-text-lowres.pdf.
- ↑ Elhaik, E (1 Jan 2013). "The missing link of Jewish European ancestry: Contrasting the Rhineland and the Khazarian hypotheses". Genome Biology and Evolution 5 (1): 61–74. doi:10.1093/gbe/evs119. PMID 23241444. PMC 3595026. http://gbe.oxfordjournals.org/content/5/1/61.
- ↑ Das, R (19 Apr 2016). "Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz". Genome Biology and Evolution 8 (7): 1132–49. doi:10.1093/gbe/evw046. PMID 26941229. PMC 4860683. http://gbe.oxfordjournals.org/content/8/4/1132.full.pdf+html.
- ↑ Elhaik, E (5 Aug 2016). "In search of the judische Typus: a proposed benchmark to test the genetic basis of Jewishness challenges notions of "Jewish biomarkers"". frontiers in Genetics 7 (141): 141. doi:10.3389/fgene.2016.00141. PMID 27547215.
- ↑ Elhaik, E (1 Jan 2013). "The missing link of Jewish European ancestry: Contrasting the Rhineland and the Khazarian hypotheses". Genome Biology and Evolution 5 (1): 61–74. doi:10.1093/gbe/evs119. PMID 23241444. PMC 3595026. http://gbe.oxfordjournals.org/content/5/1/61.
- ↑ Marshall, S (16 Nov 2016). "Reconstructing Druze population history". Scientific Reports 6 (35837): 35837. doi:10.1038/srep35837. PMID 27848937. Bibcode: 2016NatSR...635837M.
- ↑ Keys, David (20 April 2016). "Scientists reveal Jewish history's forgotten Turkish roots". The Independent. https://www.independent.co.uk/news/science/archaeology/scientists-reveal-jewish-historys-forgotten-turkish-roots-a6992076.html.
- ↑ Editorial: Population Genetics of Worldwide Jewish People, Frontiers in Genetics 28 July 2017
- ↑ Ranajit Das, Paul Wexler, Mehdi Pirooznia and Eran Elhaik, 'The Origins of Ashkenaz, Ashkenazic Jews, and Yiddish,'Frontiers in Genetics 21 June 2017
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